In the present study we examine the potential use of oligonucleotide probes to characterize Neisseria meningitidis serotypes without the use of monoclonal antibodies (MAbs).Antigenic diversity on PorB protein forms the pothys slogan in english bases of serotyping method.However, the current panel of MAbs underestimated, by at least 50% the PorB var
Abnormal processing of TAR DNA binding protein 43 (TDP-43) has been identified as a major factor in neuronal degeneration during amyotrophic lateral sclerosis (ALS) or frontotemporal lobar degeneration (FTLD).It is unclear how changes to TDP-43, including nuclear to cytosolic translocation and subsequent accumulation, are controlled in these diseas
Natural Hazard triggering fr9225 Technological Disasters (NaTech) are accidents resulting from natural hazards, such as earthquakes, interacting with industrial risks.Seismic damage to the equipment of industrial plants can lead to major accidents such as explosions, fires or hazardous releases.In this framework, the cylindrical liquid storage tank
Many proteins and signaling pathways are present in most cell types and tissues and yet perform specialized functions.To elucidate momo loungefly mechanisms by which these ubiquitous pathways are modulated, we overlaid information about cross-cell line protein abundance and variability, and evolutionary conservation onto functional pathway componen